The agriculture sector and other agribusinessescan have a long-lasting effect on the environment. The present studyinvestigates the effect of Agricultural Supply Chain Management (ASCM), fromproducer to consumer, on Environmental Sustainability (ES) in the Alkharj governorateby collecting primary data from 312 respondents in the ASCM in Alkharj and byapplying Structural Equation Modelling (SEM). Moreover, the moderating roles ofeconomic and social sustainability in the nexus between ASCM and the ES arealso tested. The results of the analyses show that ASCM directly improves theES in the agriculture sector. Moreover, ASCM also improves both economic andsocial sustainability. Consequently, economic and social sustainability improvesthe ES. Thus, economic and social sustainability have positively moderated therelationship between ASCM and the ES. The results suggest that the governmentof Alkharj governorate should further improve the economic sustainability ofagribusinesses in Alkharj by providing incentives. Moreover, education andtraining programs should be initiated to improve social sustainability. Thus,both improved social and economic sustainability of agribusinesses could encouragesustainable practices to promote the ES in the whole ASCM in Alkharj.

Pyrazoles are highly versatile and find applications in various industries including chemicals, pharmaceuticals, polymers, medications, and agriculture. Pyrazoles and their analogues exhibit a range of biological activities, including anti-inflammatory, anti-tuberculosis, antibacterial, antifungal, anti-cancer, and anti-diabetic effects. In this context, this investigation focuses on the synthesis of pyrazoles containing heterocyclic components using Amberlite resin in reactions with ultrasonic irradiation. Synthesized pyrazoles containing heterocyclic components are intermediates of the apixaban API. Some pyrazole derivatives are key impurities of the apixaban API, which is synthesized by a multistep chemical conversion and has been reported previously. The use of the heterogeneous Amberlyst resin, which acts as a reusable catalyst and is gentle on reactions, allows for a more sustainable solution that reduces costs, accelerates reactions, and shortens reaction times. The procedures for using Amberlyst resin under ultrasonic irradiation to synthesize pyrazole derivatives are cost-effective, energy-efficient, and environmentally friendly for chemical synthesis and material preparation. They also simplify workups and produce quality and yields comparable to or better than existing methods.

The purpose of this study is to investigate the direct effects of environmental sustainability orientation (ESO) on green supply chain management (GSCM), ESO on sustainable performance (SP), and GSCM on sustainable performance (SP). It also examines the indirect effect of GSCM on SP through the mediating role of GSCM. Moreover, it tests the moderating role of environmental collaboration (EC) between GSCM and SP. A total of 155 survey questionnaires were collected from firms with ISO 14000 certification in the manufacturing sector in Algeria. The gathered data was examined using (PLS-SEM) model. The findings showed positive effects between ESO, GSCM, and SP. However, no such effect was detected for the moderating role of environmental collaboration on the links between GSCM and SP. The limitation of this study was the use of only firms with ISO 14000 certification, so future studies should consider a wider range of firms and different scales. Regarding environmental problems, firms in Algeria can apply ESO and GSCM to achieve sustainable performance.

Nitrones are an interesting group of organic compounds due to their spin-trapping properties. These chemical compounds are also useful building blocks via cycloaddition reactions. In this work, a comprehensive study about correlation of selected parameters come from quantum chemical and experimental studies, namely 1H chemical shifts, IR absorption bands and UV-Vis maximum absorptions as well as reactivity descriptors such as global electrophilicity and nucleophilicity with substituent constants of Hammett, Taft, Brown and Okamoto's as well as Exner for para substituent analogues of (Z)-C-phenyl-N-methylnitrones have been study. Based on presented results it should be noted that tested models of substituent constants correlate in a satisfactory way with computational data. The opposite conclusion is observed for spectral data derived from analysis performed for synthesized nitrones. The obtained results constitute a useful element for future research on reaction mechanisms involving the tested nitrones.

This study aims to explore the effect of data analytics quality on company sustainability through operational performance as an intervening variable of Fintech Peer to Peer Lending (P2P) companies registered and licensed at the Financial Services Authority (known as OJK) Indonesia. This study is quantitative research using primary data collected through questionnaires and interviews. The data came from 104 company leaders and involved 91 Fintech P2P Lending companies registered and licensed at OJK until December 2023. Data were processed using statistical tools Structural Equation Modeling (SEM)-Lisrel. The result of processed data indicates that data analytics quality has a positive and significant effect on company sustainability through operational performance as an intervening variable. Data analytics quality with AI-based automation makes repetitive work operations easy, efficient and effective which has implications for increasing the sustainability opportunities of fintech companies.

Fourteen novel 4-(5-amino-4-cyano-1,3-oxazol-2-yl)benzenesulfonamides have been designed, synthesized, and characterized by spectroscopy and spectrometry methods. They have also been investigated on the NCI-60 cancer cell lines. The most activity compounds, 2, 3, and 9, in concentration 10 µM demonstrated mean GI50 values of 77, 70, and 68%, respectively, against the tumor cells. The best activity compound 2 showed the following GI50 values: non-small cell lung cancer (HOP-92) - 4.56 µM, breast cancer (MDA-MB-468) - 21.0 µM, melanoma (SK-MEL-5) - 30.3 µM. Besides, this compound indicates low toxicity with TGI and LC50 values >100 µM against all cancer cell lines. The COMPARE analysis (NCI) of compound 2 showed a very high correlation (r=0.91) with Tamoxifen as a selective estrogen receptors modulator. Molecular docking studies of ligand 2 demonstrated the complexation with estrogen receptors as a possible antitumor mechanism. The ADMET analysis of compound 2 indicates an optimistic prediction as an antitumor agent.

The present study analyzed the relationship between the average annual temperature and the area of Amazonian forest in the departments of Peru during the period 2013-2021, using a panel data model with random effects. The data used come from the National Institute of Statistics and Informatics (INEI) and include the average annual temperature in degrees Celsius and the area of Amazonian rainforest in thousands of hectares, both disaggregated by department. Additionally, CO2 emissions resulting from the loss of tree cover, measured in megatons (Mt) of carbon dioxide equivalent (CO₂e), were considered as a control variable. The results revealed a positive and statistically significant relationship between the area of Amazonian forest and the average annual temperature, denoting that an increase of one thousand hectares in the extension of the forest corresponds to an increase of 0.0004 °C in temperature. In this sense, the finding contradicts the climate-regulating role played by forests, however, this is attributed to the influence of unobserved confounding variables that are linked to both forest area and temperature.

Job satisfaction and digital talent are topics of growing interest in the context of digital transformation. Digitalization is changing the way organizations operate and how employees perceive their work. The state and its administrative staff is no exception, as these capabilities are essential to perform operational tasks that underpin the public institution's documentary processes. This study investigates the influence of digital talent (independent variable) on job satisfaction (dependent variable), employing structural equation modeling (SEM) using WarpPLS software. Digital Talent is broken down into three sub-variables: Digital Competencies of Employees (DCE), Capacity for Digital Innovation and Creativity (CIDC) and Adaptability and Continuous Learning (ACL), while Job Satisfaction is measured through two sub-variables: Work Environment (WE) and Professional Development Opportunities (PDO). The analyses revealed that Capacity for Innovation and Digital Creativity (CIDC) has a significant impact on Work Environment, with a path coefficient (β) of 0.13 (p = 0.01). Similarly, adaptability and continuous learning (ACL) positively influence the work environment, with a path coefficient (β) of 0.10 (p = 0.04). In addition, a strong relationship was found between professional development opportunities (PDO) and work environment, with a path coefficient (β) of 0.68 (p < 0.001). For the relationship between digital competencies (DCE) and career development opportunities, the path coefficient was 0.10 (p = 0.04). Digital talent is a key predictor of job satisfaction in administrative staff. The results suggest that investing in the development of digital capabilities, especially innovation and creativity, as well as adaptability, is essential to improve the work environment and career development opportunities.

The current work involves the synthesis of amalgamated heterocyclic scaffolds embracing pyrazolone and triazole nuclei. The suggested methodology leads to streaming in the targeted synthesis in a multicomponent reaction manner resulting in 91% yield of the structural motifs. This strategy makes use of the click reaction mechanism of copper-catalyzed azide-alkyne (CuAAC) cycloaddition. The structures of all the synthesized compounds were ascertained considering spectro-analytical data from 1H NMR, ¹³C NMR, and FTIR and Mass studies. Subsequently, molecular docking studies were performed taking into account the P. gingivalis as the heme binding targeted protein.

This study investigates the factors influencing the actual usage of freight forwarding services in Indonesia, focusing on the roles of desire, outcome expectancy, and perceived self-efficacy, with delivery risk and perceived trust acting as moderating factors. Grounded in Social Cognitive Theory (SCT), this study examines how personal cognitive factors and external risks influence users' attitudes and behaviors toward freight forwarding services. Data were collected from 616 respondents across Jakarta, Surabaya, and Makassar utilizing a structured questionnaire. Partial Least Squares Structural Equation Modeling (PLS-SEM) was employed to test the hypothesized relationships. The findings reveal that desire significantly influences both attitude and delivery risk, while attitude has a strong direct effect on actual usage. Outcome expectancy and perceived self-efficacy demonstrated weaker effects, particularly on attitudes, suggesting that other factors, such as trust and risk perceptions, play a more significant role in this context. Additionally, delivery risk was found to moderate the relationship between desire and attitude, while perceived trust did not moderate the link between attitude and actual usage. The research underscores the importance of trust-building and risk mitigation strategies for freight forwarding service providers in Indonesia. The study also provides theoretical contributions by applying SCT to the logistics sector and offers practical implications for enhancing service adoption in emerging markets.