Growing Science » Current Chemistry Letters » Use of the compound (2-(4-chlorophenyl)-3-hydroxy-4H-chromene-4-one) as a ligand complex formation by copper (II)

Journals


CCL Volumes


Current Chemistry Letters

ISSN 1927-730x (Online) - ISSN 1927-7296 (Print)
Quarterly Publication
Volume 11 Issue 4 pp. 353-358 , 2022

Use of the compound (2-(4-chlorophenyl)-3-hydroxy-4H-chromene-4-one) as a ligand complex formation by copper (II) Pages 353-358 Right click to download the paper Download PDF

Authors: Itnawita Itnawita, Zamri Adel, Ganis Fia Kartika, Sofia Anita, T. Abu Hanifah, G.A. Guntur, U. Shyfaa

DOI: 10.5267/j.ccl.2022.6.002

Keywords: Flavonol Chloride, Chalcone, Complex, Ligand

Abstract: Flavanol compounds are chalcone derivatives, generally found in hydroxy substituted forms that can act as ligands. Hydroxy-substituted flavonols are found in many plants but in very small amounts. In order to enrich and expand the use of this compound as a ligand, the synthetic methods were carried out through structural variations, one of which was by substitution using chloride and then the compound (2-(4-chlorophenyl)-3-hydroxy-4H-chromene-4-one) was obtained. In this research, the study was conducted using the compound (2-(4-chlorophenyl)-3-hydroxy-4H-chromene-4-one) as a ligand for complex formation with copper (II). From the results of the study, the mole ratio of the ligand with copper (II) metal was 2:1, pH 7.01 with a complex stability time of 15-25 minutes. The complex formed is bright yellow in color and soluble in chloroform. From the characterization of the resulted complex, it was appeared that Cu-flavonol chloride with UV-Vis spectrophotometer showed maximum absorption at wavelengths 273 and 429 indicating the presence of benzoyl and cinnamoyl peaks, with FT-IR showing the wave number 1545cm-1 indicating the presence of Cu=O-Cu bonds and absorption at 682 cm-1 indicating the presence of Cu-O bonds.

How to cite this paper
Itnawita, I., Adel, Z., Kartika, G., Anita, S., Hanifah, T., Guntur, G & Shyfaa, U. (2022). Use of the compound (2-(4-chlorophenyl)-3-hydroxy-4H-chromene-4-one) as a ligand complex formation by copper (II).Current Chemistry Letters, 11(4), 353-358.

Refrences

1. Farhan S. A. (2013) Study on the interaction of copper (II) complex of morin and its antimicrobial effect, Int. J. Chem. Sci., 11 (3) 1247-1255.
2. Jadhav S. B., Bagul K. R., Bagul P. R., and Gaikwad K. V. (2008) Synthesis of some novel flavonol derivatives and its microbial activity, Orien. J. Chem., 24 (2) 583-588.
3. Alexiou A. D., Silva D. D., Romoff P., and Ferreira M. J. (2016) Tris (3, 7-dihydroxyflavonolate-κO3, O4) chromium (III) Complex, Molbank, 2016 (1) M886.
4. Dolatabadi J. E. N., Mokhtarzadeh A., Ghareghoran S. M., and Dehghan G. (2014) Synthesis, characterization and antioxidant property of quercetin-Tb (III) complex, Adv. pharm. bull., 4 (2) 101-104.
5. Kandioller W., Balsano E., Meier S. M., Jungwirth U., Göschl S., Roller A., ... and Hartinger C. G. (2013) Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity, Chem. Comm., 49 (32) 3348-3350.
6. Destria M., Widiyantoro A., and Jayuska A. (2019) Senyawa Flavonoid dari Fraksi Diklorometana Buah Mangga Golek (Mangifera spp.) sebagai pengompleks Fe2+, Jurnal Kimia Khatulistiwa, 8 (1).
7. Abdelhamid A. A, Salama K. S. M., Elsayed A. M., Gad M. A., and El-Remaily M. A. A. A. (2022) Synthesis and Toxicological effect of some new pyrrole derivatives as prospective insecticidal agents against the cotton leafworm, spodoptera littoralis (Boisduval), ACS Omega, 7 (2022) 3990-4000.
8. Abdelhamid A. A., Elwassimy M. M., Aref S. A., and Gad M. A. (2019) Chemical design and bioefficacy screening of new insect growth regulators as potential insecticidal agents against spodoptera littoralis (Boisd.). Biotech. rep., 24 (2019) 394-401.
9. Ikhtiarudin I., Frimayanti N., Teruna H. Y., and Zamri A. (2017) Microwave-Assisted Synthesis, Molecular Docking Study and In Vitro Evaluation of Halogen Substituted Flavonols Against P388 Murine Leukemia Cells, App. Sci. Tech., 1 (1) 375-381.
10. Łapczuk-Krygier, A., Korotaev, V. Y., Barkov, A. Y., Sosnovskikh, V. Y., Jasińska, E., and Jasiński, R. (2014) A DFT computational study on the molecular mechanism of the nitro group migration in the product derived from 3-nitro-2-(trifluoromethyl)-2H-chromene and 2-(1-phenylpropylidene) malononitrile, J. Fluorine Chem., 168, 236-239.
11. Fernando F. (2017) Sintesis dan karakterisasi senyawa kompleks tembaga (II) – flavonolat tersubstitusi klorida, Universitas Riau, Pekanbaru.
12. Suciningrum E. (2011) Sintesis dan Karakterisasi Kompleks Tembaga (II) dengan Difenilamin, Universitas Sebelas Maret, Surakarta.
13. Říha M., Karlíčková J., Filipský T., Macáková K., Rocha L., Bovicelli P., … and Mladěnka P. (2014) In vitro evaluation of copper-chelating properties of flavonoids, Rsc Advances, 4 (62) 32628-32638.
14. Elhady, O., Mansour, E., Elwassimy, M., Zawam, S., Drar, A., and Abdel-Raheem, S. (2022) Selective synthesis, characterization, and toxicological activity screening of some furan compounds as pesticidal agents, Curr. Chem. Lett., 11 (3) 285-290.
15. Tolba, M. S., Sayed, M., Kamal El-Dean, A. M., Hassanien, R., Abdel-Raheem Sh, A. A., and Ahmed, M. (2021) Design, synthesis and antimicrobial screening of some new thienopyrimidines, Org. Comm., 14 (4) 334-345.
16. Abdel-Raheem, S., El-Dean, A., Hassanien, R., El-Sayed, M., Abd-Ella, A., Zawam, S., and Tolba, M. (2022) Synthesis of new distyrylpyridine analogues bearing amide substructure as effective insecticidal agents, Curr. Chem. Lett., 11 (1) 23-28.
17. Abdel-Raheem, S. A., El-Dean, A. M. K., Hassanien, R., El-Sayed, M. E., and Abd-Ella, A. A. (2021) Synthesis and characterization of some distyryl derivatives for agricultural uses, Eur. Chem. Bull., 10 (1) 35-38.
18. Tolba, M., El-Dean, A., Geies, A., Radwan, S., Zaki, R., Sayed, M., ... and Abdel-Raheem, S. (2022) An overview on synthesis and reactions of coumarin based compounds. Curr. Chem. Lett., 11 (1) 29-42.
19. Tolba, M., El-Dean, A., Ahmed, M., Hassanien, R., Sayed, M., Zaki, R., ... and Abdel-Raheem, S. (2022) Synthesis, reactions, and applications of pyrimidine derivatives, Curr. Chem. Lett., 11 (1) 121-138.
20. Abd-Ella, A., Metwally, S., El-Ossaily, Y., Elrazek, F., Aref, S., Naffea, Y., and Abdel-Raheem, S. (2022) A review on recent advances for the synthesis of bioactive pyrazolinone and pyrazolidinedione derivatives, Curr. Chem. Lett., 11 (2) 157-172.
21. Abdel-Raheem, S., El-Dean, A., Abd-Ella, A., Al-Taifi, E., Hassanien, R., El-Sayed, M., ... and Bakhit, E. (2021) A concise review on some synthetic routes and applications of pyridine scaffold compounds, Curr. Chem. Lett., 10 (4) 337-362.
22. Ensafi A. A., Taei M., and Khayamian T. (2009) A differential pulse voltammetric method for simultaneous determination of ascorbic acid, dopamine, and uric acid using poly (3-(5-chloro-2-hydroxyphenylazo)-4, 5-dihydroxynaphthalene-2, 7-disulfonic acid) film modified glassy carbon electrode, J. Elect. Chem., 633 (1), 212-220.
23. Wade L. G. (2010). Reactions of Alcohols. Organic Chem., 6, 494-495.
24. Hasan A., and Pandey L. M. (2018) Self-assembled monolayers in biomaterials, in: Narayan R. (Ed) Nanobiomaterials (pp. 137-178). Woodhead Publishing, Chambridge.
25. De Souza R. F., and De Giovani W. F. (2004) Antioxidant properties of complexes of flavonoids with metal ions. Redox Report, 9 (2), 97-104.

Journal: Current Chemistry Letters | Year: 2022 | Volume: 11 | Issue: 4 | Views: 853 | Reviews: 0

Related Articles:

Add Reviews

Name:*
E-Mail:
Review:
Bold Italic Underline Strike | Align left Center Align right | Insert smilies Insert link URLInsert protected URL Select color | Add Hidden Text Insert Quote Convert selected text from selection to Cyrillic (Russian) alphabet Insert spoiler
Security Code: *

® 2010-2024 GrowingScience.Com