Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)

Elhady, O.; Mansour, E.; Elwassimy, M.; Zawam, S.; Drar, A.

Growing Science » Current Chemistry Letters » Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)

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Current Chemistry Letters

ISSN 1927-730x (Online) - ISSN 1927-7296 (Print) Quarterly Publication Volume 11 Issue 1 pp. 63-68 , 2022

Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) Pages 63-68 Download PDF

Authors: Omar M. Elhady, Erian. S. Mansour, M. M. Elwassimy, Sameh A. Zawam, Ali M. Drar

DOI: 10.5267/j.ccl.2021.9.005

Keywords: Spodoptera littoralis (Boisd.), Tebufenozide (Mimic), Tertiary butylhydrazine hydrochloride, Synthesis

Abstract: Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center of mimic analogues was performed for compounds N-tert-butyl-2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide (2) and N-tert-butyl-2,4-dichloro-N'-[(2,4-dichlorophenyl)carbonothioyl]benzenecarbothiohydrazide (6). The toxicological study was done by using 2nd and 4th instar larvae of the cotton leaf worm, Spodoptera littoralis (Boisd.). Five concentration levels (600, 300, 150, 75 and 37.5 ppm) of compounds (2) and (6) were applied on the fresh plant food to the newly grown (2^nd and 4^th) instar larvae.

How to cite this paper

 Elhady, O., Mansour, E., Elwassimy, M., Zawam, S & Drar, A. (2022). Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.).Current Chemistry Letters, 11(1), 63-68.

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