This study investigates the influences of job demands, work exhaustion, and job satisfaction on turnover intention among Vietnamese civil service employees. Additionally, the correlation between social support and job motivation with job satisfaction and turnover intention are also examined. A structural equation modeling technique was employed to conduct the data analysis with a survey of 318 civil service employees working in 10 different departments in the public sector. The results reveal that job demands had a positive association with both work exhaustion and turnover intention. In contrast, work exhaustion and job satisfaction are both significantly related to turnover intention. Surprisingly, the adverse effects of social support and job motivation on work exhaustion are insignificant. In addition to theoretical high-lights, our study provides practical implications and managerial recommendations for government agencies in the public sector to minimize the turnover rate and retain their employees.