A famous cisplatin anticancer agent is one of the most widely used chemotherapeutics for treating several human solid tumors. Toxicity of the normal cell is a life-threatening issue that restricts the therapeutic potential of cisplatin complex as an anticancer drug. Even though every year thousands of cisplatin-based analogs have been prepared, screened, and reported, only very few compounds entered the medical trials. Hence, new research work is still sensible. In the last few years, many mononuclear and polynuclear platinum complexes have been considerably investigated, in vitro and in vivo studies evaluated, with some compounds demonstrating significant anticancer potential. In this review, various mono-metallic and poly-metallic platinum‐based complexes with various derivatives used as ligands that have anticancer potential are defined and numerous typical examples are discussed briefly. Present investigation, numerous mononuclear cisplatin derivatives exhibited greater anticancer potency than the parent cisplatin drug. However, polynuclear cisplatin derivatives showed much better anticancer activity than mononuclear cisplatin analogs against various cancer cell lines.

Caring for cancer patients may create several negative emotions for their family members. Therefore, reducing or alleviating negative feelings are essential in improving mental and physical health of cancer patients’ family members. This research aims to identify the priority levels of the strategies used by cancer patients’ family members to cope with negative emotions, utilizing Analytic Hierarchy. Next, the proposed model is applied in the cases of Vietnamese cancer patients’ family members. Four groups of coping strategies against negative emotions of cancer patients’ family members are used in the model, including: (1) positive emotion-focused coping strategies; (2) negative emotion-focused coping strategies; (3) positive action-focused coping strategies; (4) negative action-focused coping strategies.