Creating and maintaining a healthy organization is a major challenge of organizational leaders in the current volatile and competitive business environment. One of the critical aspects of a healthy organization is employees’ mental wellbeing. Aspects like workplace spirituality and mindfulness are now highly popular among organizations. However, studies linking these variables with employees’ wellbeing is an area that has not received adequate research attention. The pivotal objective of this study is to explore the combined effect of mindfulness and workplace spirituality on employees’ mental wellbeing. A cross-sectional research design was adopted for the study, and data were collected from 333 full-time employees working in diverse industries. Results reveal significant relationship between the three variables. It was also found that both workplace spirituality and mindfulness were significant predictors of mental wellbeing. The present study, enriches the literature by contributing towards an understanding of the causative factors of employees’ mental wellbeing and how it can be improved in the organizations.

Data Center energy usage has risen dramatically because of the rapid growth and demand for cloud computing. This excessive energy usage is a challenge from an economic and environmental point. Virtual Machine Placement (VMP) along with virtualization technologies is widely used to manage power utilization in data centers. The assignment of virtual machines to physical machines affects energy consumption. VMP is a process of mapping VMs onto a set of PMs in a data center to minimize total power consumption and maximize resource utilization. The VMP is an NP-hard problem due to its constraints and huge combinations. In this paper, we formulated the problem as a single objective optimization problem in which the objective is to minimize the energy consumption in cloud data centers. The main contribution of this paper is hybrid and adaptive harmony search algorithm for optimal placements of VMs to PMs. HSA with adaptive PAR settings, simulated annealing and local search strategy aims at minimizing energy consumption in cloud data centers with satisfying given constraints. Experiments are conducted to validate the performance of these variations. Results show that these hybrid HSA variations produce better results than basic HSA and adaptive HSA. Hybrid HS with simulated annealing, and local search strategy gives better results than other variants for 80 percent datasets.

In the current paper, the authors are intended to manufacture the aluminum based metal matrix composite (MMC) employing the stir casting process. Further, the fabricated composite sample is investigated for machining characteristics during the die sink electrical discharge machining process (EDM). EDM is most commonly employed to satisfy the special needs of industry such as developing deep holes and complex contours from high strength materials such as composites, alloys, smart materials, and functionally graded materials. In the current study A356 and 4%, tungsten carbide (WC) powder are considered as matrix and strengthening materials respectively to fabricate the MMCs. During the machining activity, the input factors like discharge current (Ip), Voltage (Vg), Pulse On-Time (Ton), and flushing pressure (P) are optimized for achieving optimum surface roughness (SR), Tool Wear Rate (TWR) and Material Removal Rate (MRR). To estimate the ideal set of process factors grey regression analysis (GRA) is used. From the results, it was observed that the GRA is found to perform better than the RSM.

The intention of this paper is to propose some similarity measures between Fermatean fuzzy sets (FFSs). Firstly, we propose some score based similarity measures for finding similarity measures of FFSs and also propose score based cosine similarity measures between FFSs. Furthermore, we introduce three newly scored functions for effective uses of Fermatean fuzzy sets and discuss some relevant properties of cosine similarity measure. Fermatean fuzzy sets introduced by Senapati and Yager can manipulate uncertain information more easily in the process of multi-criteria decision making (MCDM) and group decision making. Here, we investigate score based similarity measures of Fermatean fuzzy sets and scout the uses of FFSs in pattern recognition. Based on different types of similarity measures a pattern recognition problem viz. personnel appointment is presented to describe the use of FFSs and its similarity measure as well as scores. The counterfeit results show that the proposed method is more malleable than the existing method(s). Finally, concluding remarks and the scope of future research of the proposed approach are given.

The Zinc doped calcium borate (Zn-CaB) was synthesized by the co-precipitation method. Zinc was known to exhibit a good antimicrobial effect without causing any environmental issues. However, the antimicrobial activity of zinc is relatively low as compared to silver or copper analogues. In the present investigation, an attempt was made to incorporate zinc in the matrix of calcium borates to enhance the antibacterial effect. Cosmetic products were made using the zinc-calcium-borates and the antibacterial/antifungal activity was evaluated and compared with the commercial products. The studies revealed that the antibacterial activity of Zn-CaB was equivalent to that commercially available product with a maximum of 99% reduction in bacterial strains and above 95% reduction in fungal strains. An attempt was made to incorporate a bacteriostatic effect on fabric by adding zinc-calcium-borates to detergent which exhibited prolonged antibacterial activity, even after 3 washing cycles. The cosmetic products were also evaluated for their thermal and photostability.

In most of the machining processes, the complexity arises in the selection of the right process parameters, which influence the machining process and output responses such as machinability and surface roughness. In such situations, it is important to estimate the inter-relationships among the output responses. One such method, Decision-Making Trial and Evaluation Laboratory (DEMATEL) is applied to study the inter-relationships of the output responses. Estimation of proper weights is also crucial where the output responses are conflicting in nature. In the current study, DEMATEL technique is used for estimating the inter-relationships for output responses in machining of EN 24 alloy under dry conditions. CRiteria Importance Through Inter-criteria Correlation (CRITIC) method is used to estimate the weights and finally the optimal selection of machining parameters is carried out using Techniques for Order Preference by Similarity to an Ideal Solution (TOPSIS) method. The model developed guides the decision maker in selection of precise weights, estimation of the inter relationships among the responses and selection of optimal process parameters.

A series of N-acetyl pyrazole derivatives, 1-acetyl-3-aryl-5-[5'-(4-nitrophenyl)-2'-furyl]-4,5-dihydro-1H-pyrazoles (5a-j) were synthesized by cyclocondensation reaction between 1-aryl-3-[5-(4-nitrophenyl)-2-furyl]prop-2-en-1-ones (4a-j) and hydrazine hydrate in glacial acetic acid at reflux temperature. Before that, compounds (4a-j) were synthesized by the condensation of 5-(4-nitrophenyl) furan-2-carbaldehyde (3) with various aromatic ketones by using alkali as catalyst. The constitution of the synthesized products has been characterized by using elemental analysis, Infrared,¹H-NMR, ¹³C-NMR spectroscopy and further supported by Mass spectroscopy. All the products have been screened for their in-vitro biological assay like antibacterial activity towards Gram-positive and Gram-negative bacterial strains and antifungal activity towards Aspergillus niger at a concentration of 40 µg/ml. It was exposed that the compounds 5a, 5b, 5c, 5d, 5g, 5h and 5j showed motivating antibacterial and antifungal activity compared to the used reference standard.

In this work, we studied the problem of thermoelastic diffusion beams on the basis of modified couple stress theory under the effects of two temperature and laser pulse. The Euler-Bernoulli beam theory and the Laplace transform technique are applied to solve the basic equations of thermoelastic diffusion in the non-dimensional form. The transformed components of displacement, lateral deflection, axial stress, temperature change, concentration, and chemical potential are calculated mathematically to solve the problem. Copper material is used to prepare the mathematical model. The general algorithm of the inverse Laplace transform technique has been calculated numerically. MATLAB software is used to find the results numerically and depict them graphically. The effects of two temperature, laser pulse, and couple stress are presented graphically on the physical quantities. Particular cases are also discussed in the present problem. Laser pulse has many applications in Heat treatment, cutting of plastics, glasses, ceramics, semiconductors and metals, surgery, Lithography, and welding.

Flibanserin (Addyi) is a medication used to treat women who have not gone through menopause who have low sexual desire. Specific and simple stability indicating method was developed and validated by high-performance liquid chromatography (RP-HPLC) for the determination of Flibanserin. Separation was carried out by using a mobile phase consisting of 0.01M Potassium phosphate monohydrate buffer (KH₂PO₄) pH 3.50 buffer: Acetonitrile in the ratio of 60:40. The column used was Agilent C18, (150×4.6) mm, 5µm with a flow rate of 1.0ml/min and temperature at 30°C. The detection was carried out at 248 nm and Flibanserin was eluted at around 2.8min. This method was validated as per ICH guidelines and validation included specificity, precision, linearity, accuracy, forced degradation, and robustness. Forced degradation was conducted under the conditions of hydrolysis, oxidation, thermal, acid, base, and peroxide hydrolysis. The calibration curve was linear over the concentration range from 20 to 200µg/mL and the coefficient of determination (r²) was observed as 0.9998. The precision and accuracy of the method were within the acceptable range. The results of this study showed that the validated method is simple and accurate, which confirmed that the method is suitable for the determination of Flibanserin.

The present manuscript describes an in-depth analysis of various interactions present in the crystal structure of formyl coumarins using Crystal explorer 17.0. Element based interactions were quantified by the decomposition of generated 3D surfaces into 2D fingerprint regions. DFT methods were used to explore electrostatic parameters, global and local reactivity descriptors. Electrophilicity based charge transfer (ECT) analysis was done to explore the probability of charge transfer between formyl coumarins and DNA base pairs. The reactivity and selectivity of different formyl coumarins have been accessed using Fukui functions in their reduced form. Non-bonding orbital (NBO) analysis revealed the presence of various hyperconjugative interactions and their stabilization energy in formyl coumarins. Non-linear optical properties are presented in terms of first order hyperpolarizibility (β₀), where maximum β₀ is observed for C4 (1.64 × 10-30esu.) which is found to be 2 times greater than that of p-nitroaniline. Molecular electrostatic potential (MEP) plots are mapped in terms of electron density.