This study aims to assess the influence of green HR management and Green Supply Chain on practices for initiating green business and environmental sustainability. The research also incorporated the mediation role of environmental sustainability between green HR practices, Green Supply Chain, and green business. A structural study methodology was used with 220 samples drawn from manufacturing companies in the province of Central Java. A questionnaire was used to collect data. The PLS(SEM) was also utilized to assess the constructs' reliability and validity as well as investigate their hypothesized links. The finding of this study indicates that environmental sustainability significantly mediates the relationship between green HRM, green supply chain, and green business. The research also finds a positive relationship between green HRM, environmental sustainability, and green businesses. Similarly, findings also found a significant relationship between green supply chain, environmental sustainability, and green industries. The results of this study can be applied to strengthen the resource based theory and literature of HRM and supply chain management. There are several practical managerial implications for improving the performance of manufacturing companies in Central Java. They provide recommendations for practitioners and managers to improve the business performance of companies based on green HRM, green supply chain, and environmental sustainability.