Autocorrelation and measurement errors have a negative effect on the performance of any monitoring scheme; therefore, more efficient monitoring schemes are required to monitor such special processes. Hence, in this paper, the use of improved synthetic and runs-rules X̅ schemes with an embedded variable sample size and sampling interval (VSSI) approach to efficiently monitor the mean of a process under the combined effect of autocorrelation and measurement errors is proposed. These new monitoring schemes incorporate a linearly covariate error model with a constant standard deviation and a first-order autoregressive model to the variability of this special process in order to account for measurement errors and autocorrelation, respectively. Moreover, in order to evaluate the zero- and steady-state run-length properties of the proposed monitoring schemes, a dedicated Markov chain matrix that takes into account the following is constructed: (i) VSSI approach, (ii) improved charting regions design of the synthetic and runs-rules X̅ schemes, and (iii) the combined effect of autocorrelation and measurement errors. Also, the probability elements of the Markov chain matrix incorporate two special sampling methods that aid in the reduction of the negative effect of autocorrelation and measurement errors. A real life example is given to illustrate the implementation of the proposed monitoring schemes.