Facile conversion of structurally different epoxides to the corresponding B-chlorohydrins was carried out successfully with anhydrous ZnCl2 in CH3CN. The reactions were carried out within 10-50 min to give B-chlorohydrins with perfect regioselectivity and high yields (80-97%).
Growing Science » Tags cloud » Regioselective
1. 
Anhydrous ZnCl2: A Highly Efficient Reagent for Facile and Regioselective Conversion of Epoxides to B-Chlorohydrins Pages 19-26
Download PDF
Authors: Ronak Eisavi, Behzad Zeynizadeh, Mehri Kouhkan
DOI: 10.5267/j.ccl.2015.10.001
Keywords: Anhydrous ZnCl2, B-Chlorohydrin, Epoxide, Regioselective
Abstract:
Journal: CCL | Year: 2016 | Volume: 5 | Issue: 1 | Views: 2015 | Reviews: 0
2.
Regioselective synthesis of 3-arylpyrido[2,3-b]pyrazines by reaction of arylglyoxals with 2,3-diaminopyridine Pages 21-26
Download PDF
Authors: Jabbar Khalafy, Ahmad Poursattar Marjani, Maryam Haghipour
DOI: 10.5267/j.ccl.2012.12.003
Keywords: 2-3-Diaminopyridine, Arylglyoxals, Pyrido[2-3-b]pyrazines, Regioselective
Abstract:
A series of pyrido[2,3-b]pyrazine derivatives were synthesized in good to excellent yields by condensation reactions of arylglyoxals with 2,3-diaminopyridine in dimethylformamide and ethanol at 90 oC.
Journal: CCL | Year: 2013 | Volume: 2 | Issue: 1 | Views: 2585 | Reviews: 0
3.
Regioselective one-pot, three component synthesis of ethyl 6-aryl-3-propylpyridazine-4-carboxylates in water Pages 115-122
Download PDF
Authors: Jabbar Khalafy, Mehdi Rimaz, Mahnaz Ezzati
Keywords: Pyridazine, Arylglyoxal, Hydrazine, Regioselective
Abstract:
A regioselective synthesis of ethyl 6-aryl-3-propylpyridazine-4-carboxylates by one-pot three-component reaction of ethyl butyrylacetate with various arylglyoxals in the presence of hydrazine hydrate at room temperature in water was described.
Journal: CCL | Year: 2012 | Volume: 1 | Issue: 3 | Views: 7511 | Reviews: 0