Over the last few years, knowledge has become part of the operations, both at the productive and service level; being considered as an important resource in companies, since it can generate competitive advantage. The objective was to determine the relationship between the activities developed by the companies from Nonaka & Takeuchi's (1995) approach and the creation of qualitative and quantitative value in 150 micro-entrepreneurs from different sectors. Partial least squares regression technique was used for data analysis and the results showed a direct relationship between socialization, combination and internalization and value creation; on the other hand, the relationship between externalization and value creation was inverse. For all relationships the p-value ensured the significance of them; finally, the study proposes the generation of intra and inter-organizational relationships for the creation, dissemination and use of knowledge in companies.