The research aims to test the impact of corporate social responsibility toward employees on employee motivation in Vietnamese businesses. Based on 804 samples, results show that, be-sides the factors of opportunistic behavior, all factors of trust and social responsibility had positive impacts on employee motivation. In particular, the trust has the largest level of influence. The study also pointed out the opposite effect of the trust and social responsibility factors of enterprises toward employees on opportunistic behavior in enterprises. The authors propose a number of recommendations to increase employee motivation in businesses in emerging economies, including Vietnam.