Pandemic covid has changed the business view to be more dynamic to business performance. The policy of restricting activity also undermines business difficulties that occur, so it is necessary to find how businesses can survive wholesale. This research was conducted to determine the effect of supply chain management (SCM) on multi-channel retailing and business performance in the era of pandemic covid-19 and restrictions on community mobility. Using analysis of this research path is divided into two criteria of direct and indirect influence. This study was conducted on several wholesale shops in Indonesia with 99 respondents. The main finding of this study is that SCM can affect business performance through multi-channel retailing with three main indicators: inventory investment, inventory efficiency, and forecasting accuracy. The added value gained from this research is from the test results obtained that a good inventory management scheme and forecasting and support from many supplies and sales channels will drive business performance for the better.