The present paper aims to analyze, model and optimize regional development of rural and urban areas of Sistan & Balochestan, separately. The relationship between employment changes and growth rate of economic sections has been modeled and numbers of jobs required for providing optimum growth rate have been obtained. This paper indicates that considering the average census of five decades (1956-2006) the situation of labor market and growth rate of economic sections in urban areas are bad and worse in rural areas so that there is need to increase employment considerably in order to achieve minimum economic growth rate ( 1% growth).