The Structural Equation Modeling SEM using SmartPLS.V3 software was used in this study to model the priority of CSFs of program management under four categories (program planning, strategy of the organization, stakeholders, and construction program performance) associated with Regional Development Programs RDPs in Iraqi provinces. Based on the literature review, the identified CSFs of program management have been explored through a systematic review approach. This model investigated the relationship and effect of CSFs on program management of regional development. The measurement model underwent three iterations to fulfil the threshold criterion, which included Cronbach's a being more than 0.7, CR being greater than 0.7, and AVE being more significant than 0.5. As a result, the model met the convergent validity. For every path modelling and hypothesis, the structural model is evaluated. The model produced a GoF of (0.524), regarded as sufficiently high to be considered for obtaining adequate global PLS model validity. The model's global GoF performance was also assessed, and the findings met the criteria. It is clear from the final model that there may be a connection between the main program management groups, as shown by the path model confirmed.