This study assessed the critical success factors (CSFs) of public-sector road construction projects execution from the perspective of definitive stakeholders associated with such projects by drawing on in-depth semi-structured interviews (16) and surveys (372) in Ghana, thirty-four (34) CSFs were identified. Using Relative Importance Index (RII), Spearman Rank Correlation Coefficients, and Kendall’s Coefficient of Concordance and the Chi-square test of significance statistics, the top ten most important factors in descending order are: the absence of political interference, project continuity by successive governments, adequate project funding, support from financial institutions and donor agencies and countries, government commitment to the project, absence of clientelism, absence of nepotism, no political corruption, payments of contractors on time and absence of court injunction or legal suit and land litigations. This study contributes to road construction CSFs in the context of public sector road construction in developing economies.