The total synthesis of mycophenolic acid (MPA), a potent immunosuppressant, was modified. The obtained mycophenolic acid was suitable for further preparation of new prospective immunosuppressants with improved therapeutic properties.
Growing Science » Authors » Agnieszka Siebert
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Modifications of total synthesis of mycophenolic acid Pages 9-16
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Authors: Grzegorz Cholewinski, Magdalena Malachowska–Ugarte, Agnieszka Siebert, Michał Prejs, Krystyna Dzierzbicka
Keywords: Mycophenolic acid, Immunosuppressants, Claisen rearrangement, Oxidation, Total synthesis
Abstract:
Journal: CCL | Year: 2018 | Volume: 7 | Issue: 1 | Views: 1967 | Reviews: 0