This study aims to study the macroeconomic factors that affect the rate of return of securities in the transport and service category of the Stock Exchange of Thailand. The category comprises three groups: media services, tourism, hotel and recreation and transport and logistics. The study employs quarterly data from 2001 to 2019 estimated with the ARDL bounds testing approach. The results reveal that media services, tourism, hotel and recreation and transport and logistics groups in the tourism and service category were cointegrated with stock exchange volume (in thousands of shares), exchange rate, gold bullion price, interest rate and diesel oil price. This study also found the long-term equilibriums of the macroeconomic factors deviated from the short-run to long run for three groups. The gold bullion price factor is a major factor in determining the long run. This study suggests that the gold bullion price is an alternative indicator for investment. Investors in the transport and logistics group should focus on the exchange rate, the gold bullion price, the interest rate and the diesel oil price before investment. Investors should consider the level of the exchange rate before investing in the media service group in the Stock Exchange of Thailand while investors in the tourism, hotel and recreation group of the Stock Exchange of Thailand should be recognize the stock exchange volume.