How to cite this paper
Hawrył, A., Świeboda, R., Gawroński, M., A., W., P., P & Kocjan, R. (2015). Determination of lipophilicity of some new 1,2,4-triazole derivatives by RP-HPLC and RP-TLC and calculated methods.Current Chemistry Letters, 4(3), 101-110.
Refrences
1. Ertl P., Rohde B., and Selzer P. (2000) Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. J. Med. Chem., 43, 3714-3717.
2. Hansch C., and Fujita T. (1964) p-?-? Analysis. A Method for the Correlation of Biological Activity and Chemical Structure. J. Am. Chem. Soc., 86, 1616-1626.
3. Komsta ?., Skibi?ski R., Berecka A., Gumieniczek A., Radkiewicz B., and Rado? M. (2010) Revisiting thin-layer chromatography as a lipophilicity determination tool-a comparative study on several techniques with a model solute set. J. Pharm. Biomed. Anal., 53, 911-918.
4. Pitucha M., Polak B., Swatko-Ossor M., Popio?ek ?., and Ginalska G. (2010) Determination of the Lipophilicity of Some New Derivatives of Thiosemicarbazide and 1,2,4-triazoline-5-thione with Potential Antituberculosis Activity. Croat. Chem. Acta, 83, 299-306.
5. Plech T., Luszczki J.?., Wujec M., Flieger J., and Pizo?, M. (2013) Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1,2,4-triazoles. Eur. J. Med. Chem., 60, 208-215.
6. Briciu R.D., Kot-W?sik A., W?sik A., Namie?nik J., and S?rbu C. (2010) The lipophilicity of artificial and natural sweeteners estimated by reversed-phase thin-layer chromatography and computed by various methods. J. Chromatog. A, 1217, 3702-3706.
7. Casoni D., Kot-W?sik A., Namie?nik J., and S?rbu C. (2009) Lipophilicity data for some preservatives estimated by reversed-phase liquid chromatography and different computation methods. J. . Chromatogr. A, 1216, 2456-2465.
8. Snyder L.R., Dolan J.W., and Gant J.R. (1979) Gradient elution in high-performance liquid chromatography: I. Theoretical basis for reversed-phase systems. J. Chromatogr. A, 165, 3-30.
9. Soczewi?ski E., and Wachtmaister C.A. (1962) The relation between the composition of certain ternary two-phase solvent systems and RM values. J. Chromatogr., 7, 311-320.
10. J??wiak K., Szumi?o H., and Soczewi?ski E. (2001) Lipophilicity, methods of determination and its role in biological effect of chemical substances. Wiadomo?ci Chemiczne (in Polish), 55, 1047-1074.
11. Valko K., and Slegel P. (1993) New chromatographic hydrophobicity index (?0) based on the slope and the intercept of the log k? versus organic phase concentration plot. J. Chromatogr., 631, 49-61.
12. Pyka A. (2004) Study of lipophilicity and application of selected topological indexes in QSAR analysis of nicotinic acid derivatives. Part I. J. Planar Chromatogr., 17, 275-279.
13. Popio?ek ?., Kosikowska U., Mazur L., Dobosz M., and Malm A. (2013) Synthesis and antimicrobial evaluation of some novel 1,2,4-triazole and 1,3,4-thiadiazole derivatives; Med. Chem. Res., 22, 3134-3147.
14. Popio?ek ?., Kosikowska U., Dobosz M., and Malm A. (2012) Synthesis and Antimicrobial Properties of New Thiosemicarbazide, 1,2,4-Triazole, and 1,3,4-Thiadiazole Derivatives of Sulfanylacetic Acid. Phosphorus, Sulfur, and Silicon Relat. Elem., 187, 468-481.
15. www. molinspiration.com
16. www.organic-chemistry.org
17. www.vcclab.org
18. Ertl P. (2010) Molecular structure input on the web. J. Cheminform., 2, 1-9.
19. Jaffe H.H. (1953) A Reexamination of the Hammet Equation. Chem. Rev., 53, 191-238.
20. Snyder L.R. (1978) Classification of the Solvent Properties of Common Liquids. J. of Chromatogr. Sci., 16, 223-234.
21. Karger B.L., Snyder L.R., and Econ C. (1976) An expanded solubility parameter treatment for classification and use of chromatographic solvents and adsorbents : Parameters for dispersion, dipole and hydrogen bonding interactions. J. Chromatogr., 125, 71-88.
22. Cimpan G., Hadaruga M., and Miclaus V. (2000) Lipophilicity characterization by reversed-phase liquid chromatography of some furan derivatives. J. Chromatogr. A, 869, 49-55.
23. Casoni D., Cobzac C.S., and Sarbu C. (2010) A comparative study concerning the lipophilicity of some synthetic dyes estimated by thin layer chromatography and different computation methods.Rev. Chim., 61, 229-234.
24. Hood G.M. (2010) PopTools version 3.2.5. Available on the internet. URL, http://www.poptools.org.
2. Hansch C., and Fujita T. (1964) p-?-? Analysis. A Method for the Correlation of Biological Activity and Chemical Structure. J. Am. Chem. Soc., 86, 1616-1626.
3. Komsta ?., Skibi?ski R., Berecka A., Gumieniczek A., Radkiewicz B., and Rado? M. (2010) Revisiting thin-layer chromatography as a lipophilicity determination tool-a comparative study on several techniques with a model solute set. J. Pharm. Biomed. Anal., 53, 911-918.
4. Pitucha M., Polak B., Swatko-Ossor M., Popio?ek ?., and Ginalska G. (2010) Determination of the Lipophilicity of Some New Derivatives of Thiosemicarbazide and 1,2,4-triazoline-5-thione with Potential Antituberculosis Activity. Croat. Chem. Acta, 83, 299-306.
5. Plech T., Luszczki J.?., Wujec M., Flieger J., and Pizo?, M. (2013) Synthesis, characterization and preliminary anticonvulsant evaluation of some 4-alkyl-1,2,4-triazoles. Eur. J. Med. Chem., 60, 208-215.
6. Briciu R.D., Kot-W?sik A., W?sik A., Namie?nik J., and S?rbu C. (2010) The lipophilicity of artificial and natural sweeteners estimated by reversed-phase thin-layer chromatography and computed by various methods. J. Chromatog. A, 1217, 3702-3706.
7. Casoni D., Kot-W?sik A., Namie?nik J., and S?rbu C. (2009) Lipophilicity data for some preservatives estimated by reversed-phase liquid chromatography and different computation methods. J. . Chromatogr. A, 1216, 2456-2465.
8. Snyder L.R., Dolan J.W., and Gant J.R. (1979) Gradient elution in high-performance liquid chromatography: I. Theoretical basis for reversed-phase systems. J. Chromatogr. A, 165, 3-30.
9. Soczewi?ski E., and Wachtmaister C.A. (1962) The relation between the composition of certain ternary two-phase solvent systems and RM values. J. Chromatogr., 7, 311-320.
10. J??wiak K., Szumi?o H., and Soczewi?ski E. (2001) Lipophilicity, methods of determination and its role in biological effect of chemical substances. Wiadomo?ci Chemiczne (in Polish), 55, 1047-1074.
11. Valko K., and Slegel P. (1993) New chromatographic hydrophobicity index (?0) based on the slope and the intercept of the log k? versus organic phase concentration plot. J. Chromatogr., 631, 49-61.
12. Pyka A. (2004) Study of lipophilicity and application of selected topological indexes in QSAR analysis of nicotinic acid derivatives. Part I. J. Planar Chromatogr., 17, 275-279.
13. Popio?ek ?., Kosikowska U., Mazur L., Dobosz M., and Malm A. (2013) Synthesis and antimicrobial evaluation of some novel 1,2,4-triazole and 1,3,4-thiadiazole derivatives; Med. Chem. Res., 22, 3134-3147.
14. Popio?ek ?., Kosikowska U., Dobosz M., and Malm A. (2012) Synthesis and Antimicrobial Properties of New Thiosemicarbazide, 1,2,4-Triazole, and 1,3,4-Thiadiazole Derivatives of Sulfanylacetic Acid. Phosphorus, Sulfur, and Silicon Relat. Elem., 187, 468-481.
15. www. molinspiration.com
16. www.organic-chemistry.org
17. www.vcclab.org
18. Ertl P. (2010) Molecular structure input on the web. J. Cheminform., 2, 1-9.
19. Jaffe H.H. (1953) A Reexamination of the Hammet Equation. Chem. Rev., 53, 191-238.
20. Snyder L.R. (1978) Classification of the Solvent Properties of Common Liquids. J. of Chromatogr. Sci., 16, 223-234.
21. Karger B.L., Snyder L.R., and Econ C. (1976) An expanded solubility parameter treatment for classification and use of chromatographic solvents and adsorbents : Parameters for dispersion, dipole and hydrogen bonding interactions. J. Chromatogr., 125, 71-88.
22. Cimpan G., Hadaruga M., and Miclaus V. (2000) Lipophilicity characterization by reversed-phase liquid chromatography of some furan derivatives. J. Chromatogr. A, 869, 49-55.
23. Casoni D., Cobzac C.S., and Sarbu C. (2010) A comparative study concerning the lipophilicity of some synthetic dyes estimated by thin layer chromatography and different computation methods.Rev. Chim., 61, 229-234.
24. Hood G.M. (2010) PopTools version 3.2.5. Available on the internet. URL, http://www.poptools.org.